MSM® STENTS 2017
from MSM® – a German company
which specializes in medical devices.
MSM® stents have CE approval
and are ISO 9001 certified.
all products are Made in Germany!
MSM® DES Sirolimus
SAFETY – EFFICACY – DELIVERABILITY
The MSM Sirolimus Eluting Coronary Stent System convinces with its trusted Cobalt Chromium Platform and the largest size portfolio available.
A fully biodegradable polymer coating containing Sirolimus (Rapamycin), enables controlled drug release preventing early thrombotic events and stent restenosis.
The biocompatible PLGA Polymer provides consistent, controlled and a 100 % drug release. The Polymer degrades 100 % into carbon dioxide and water.
The decreased profile results in an increased flexibility and enables an easy side branch access.
Safety and Efficiency of Sirolimus
Effective Factor – Drug
Acting on G1 phase or M phase has different effects
Polymer Coating of MSM Sirolimus
PLGA 85/15 Biocompatible Polymer
The thickness of biodegradable polymer-coating is only 5 μm, thinner coating increases the ability and effectiveness of delivery.
Advanced Coating Technology
Advanced Surface treatment & Coating Technology
During expansion
After expansion
Factor that affects efficacy Polymer Coating
drug releasing pattern would affect the whole process of restenosis
Four courses of intimal repairing can cause restenosis
- Platelet deposition occurring in 15 days after stent implantation
- Leukocyte recruitment occurring in 50 days
- SMC migration/proliferation occurring in 90 days
- Matrix deposition occurring after 120 days
Drug Release Rate
90-days drug releasing time First 80% of drug dosage can be released in first month. This controlled drug releasing rate can effectively prevent restenosis during intimal repairing progress
MSM Sirolimus Stent Design
Well-balanced Support and Deliverability
| Material | Cobalt Chromium |
| Strut thickness | 65 μm |
| Coating thickness | 3 – 5 μm |
| Metal-artery ratio | 15% – 18% |
| Balloon tip profile | 0.017″ (0.43mm) |
| Lowest crossing profile | 0.035″ (0.90mm) |
| Recoil | >2% |
A lot of published papers* showed that the use of a thinner strut stent is associated with a significant reduction of angiographic and clinical restenosis after coronary artery stenting.
* “Intracoronary Stenting and Angiographic Results – Strut Thickness Effect on Restenosis Outcome (ISAR-STEREO) Trial” , Adnan Kastraiti MD, Albert Schömig MD, 2001; 103:2816-2821, Circulation
* “In-Stent Restenosis in Small Coronary Arteries – Impact of Strut Thickness” , Carlo Briguori MD etc., Vol. 40, No. 3, 2002, Journal of the American College of Cardiology
MSM DES Sirolimus
– Excellent Side Branch Access
open cell design with 3 interlinks per segment
Diameter of mostly used device
- Guidewire: BMW 0.014” (0.36mm)
- Balloon Dilation Catheter: 0.024” (0.61mm)
Delivery system of MSM DES Sirolimus
Nominal inflation pressure is 8 atm
- Hydrophilic coated distal shaft 1.9F shaft with a rapid deflation balloon
- The balloon design optimizes a controlled linear expansion
- A balloon overhang of <5 mm minimises vessel injury outside the stent
Technical Details Stent
| Type of design | open cell design with 3 interlinks per segment |
| Design details | 9 crown per segment |
| Material | Cobalt-Chromium L605 |
| Size Range | 2.25 mm – 4.00 mm |
| Strut thickness | 0.0026″ ( 65μm ) |
| Strut width (Main segment) | 0.0028″ ( 72μm ) |
| Strut width (interlink) | 0.0023″ ( 58μm ) |
| Shortening after expansion | < 2% |
| Recoil | < 5% |
| Sirolimus Matrix Thickness | < 18% |
| 3-5 μm | |
| Guinding Catheter compatibility | 5 F |
Technical Details Catheter
| Usable length | 138 cm |
| Length of the guide wire lumen | 27 cm |
| Material | Balloon |
| Distal shaft | Polyamide, Multi layer tubing |
| Proximal shaft | Stainless Steel with PTFE Coating |
| Shaft size | Proximal |
| Distal | 2.5 F – 2.9 F, depending on balloon size |
| Balloon folding | Balloon sizes 2.25 mm bis 2.5 mm |
| Balloon sizes 2.75 mm to 4.50 mm | 4-fold balloon |
| Marker | Embedded Platinum/ Iridium Marker |
| Tip profile | 0.017″ (0.43 mm) |
| Max. recommended guide wire | 0.014″ (0.36 mm) |
Specifications of MSM DES Sirolimus
43 and 48 mm long stent, saving for both patients and doctors
Compliance Data
Order Information
